International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 9 Issue 2
2018 (April-June)
In vitro screening of Capparishorrida L. pericarp for antimicrobial and anticancer activity
lessThan i greaterThan Capparishorrida lessThan /i greaterThan is commonly known as Indian caper, found in India, Bangladesh, Sri Lanka, Malaysia and some parts of Pakistan. lessThan i greaterThan Capparishorrida lessThan /i greaterThan belongs to the family lessThan i greaterThan Cappareaceae. lessThan /i greaterThan Almost all the parts of the plant are used for different medicinal purposes and it is used in many ayurvedic formulations. The aim of the present study is to characterize the phytochemical, antibacterial and lessThan i greaterThan in vitro lessThan /i greaterThan anticancer activity of lessThan i greaterThan Capparishorrida lessThan /i greaterThan stem extracts. Qualitative phytochemical screening tests were done using ethyl acetate, hexane and water stem extracts of lessThan i greaterThan Capparishorrida. lessThan /i greaterThan Antibacterial activity of stem bark extracts of lessThan i greaterThan Capparishorrida lessThan /i greaterThan was determined by agar well diffusion method. lessThan i greaterThan In vitro lessThan /i greaterThan antiproliferative activity of lessThan i greaterThan Capparishorrida lessThan /i greaterThan against PA-1 (ovarian cell line) was determined using MTT assay. lessThan i greaterThan In vitro lessThan /i greaterThan cytotoxic activity by MTT assay against L929 (fibroblast cell line) was also analysed. Preliminary phytochemical screening of ethylacetate, hexane and water extracts of lessThan i greaterThan Capparishorrida lessThan /i greaterThan stem revealed the presence of alkaloids, terpenoids and flavonoids. The observed inhibitory potential of the extracts towards bacteria and cancer cells could be ascribed to the presence of these secondary metabolites in the extracts.
KRISHNAVENI*, SANGEETHA
Phytoconstituents, cytotoxicity, antiproliferative, antibacterial, anticancer
17-25