<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 10 Issue 3</issue_number>
<issue_period>2019 (July-September)</issue_period>
<title><b>Evaluation of efficacy of chicken egg yolk (IgY) antibodies and <i>aloe vera</i> extract against <i>Candida albicans in vitro</i> and <i>In vivo </i>with respect to oral candidiasis</b></title>
<abstract>The present research work was aimed to produce chicken egg yolk antibodies against the whole cell antigen of  lessThan i greaterThan Candida albicans,  lessThan /i greaterThan to prepare  lessThan i greaterThan Aloe vera lessThan /i greaterThan  extract and to test their potential both  lessThan i greaterThan in vitro  lessThan /i greaterThan and  lessThan i greaterThan in vivo  lessThan /i greaterThan to control the virulence and development of the fungi. The anti- lessThan i greaterThan C.albicans lessThan /i greaterThan  IgY was tested for its efficacy to inhibit the cell growth of  lessThan i greaterThan C.albicans  lessThan /i greaterThan by growth inhibition assay. The growth of  lessThan i greaterThan C.albicans lessThan /i greaterThan  with specific IgY showed significant reduction when compared with unimmunized IgY. The ability of anti  lessThan i greaterThan C.albicans lessThan /i greaterThan  IgY and  lessThan i greaterThan Aloe vera lessThan /i greaterThan  extract to inhibit the adhesion of  lessThan i greaterThan C.albicans lessThan /i greaterThan  to KB cell lines was evaluated by adhesion inhibition assay since adhesion is the first prerequisite condition required for  lessThan i greaterThan C.albicans lessThan /i greaterThan  to induce infections. Our results indicated that they could efficiently inhibit the adherence of  lessThan i greaterThan C.albicans lessThan /i greaterThan  to the KB cells which were significantly ( lessThan em greaterThan P</abstract>
<authors>Dr.T.JEEVITHA, Dr.K.DEEPA AND Dr.A.MICHAEL</authors>
<keywords>Candida albicans, oral candidiasis, Drug Resistance, IgY antibodies, Aloe vera </keywords>
<pages>214-223</pages>
</article>
</Journal>
