10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 3 2011 (July - September) The white bulbs of 'Wild Onion lessThan b greaterThan lessThan i greaterThan , lessThan /i greaterThan lessThan /b greaterThan lessThan i greaterThan Urginea indica lessThan /i greaterThan ' samples were collected from the hillocks near Vaddagere village of Tumkur district, a southern part of Karnataka. The study was performed extensively for the first time, leading to the evaluation of active constituents from wild onion bulb. The extract was prepared with Methanol and subjected for preliminary phyto-chemical and physico-chemical analysis. The total ash content, acid insoluble and water soluble ash content were evaluated along with the fluorescence characteristics of the methanolic extract of Wild onion sps. The presence of primary and secondary metabolites such as lessThan i greaterThan carbohydrate, proteins, alkaloids, phenolic compounds, saponins lessThan /i greaterThan was confirmed through preliminary phyto-chemical analysis. The extract was found to possess anti-bacterial activity in lessThan i greaterThan E. coli, S. aureus and P. aeruginosa lessThan /i greaterThan isolated from infected patients. The Minimum inhibitory concentration (MIC) was also evaluated by 'Tube dilution' method and the result was found to be considerably effective against selected pathogenic bacteria. Such an effect might contribute to explaining the traditional use of wild onion sps, lessThan i greaterThan Urginea indica lessThan /i greaterThan in the treatment of wound healing. The antioxidant activity was estimated by using DPPH free radical scavenging assay and the activity was increased with increase in concentration of methanolic fraction of wild Onion sps. The fractions of wild onion sps are free radical scavengers and are able to react with the DPPH radical, which might be attributed to their electron donating ability and suggested that antioxidant components in this Wild Onion sps was capable of reducing oxidants and scavenging free radicals. This also indicates that, tubers of wild onion, lessThan i greaterThan Urginea indica lessThan /i greaterThan ' are of therapeutic potential due to their high free-radical scavenging activity. The presence of high amount of saponins justifies the practice of treatment for disturbances in the gastrointestinal tract by Traditional healers. The role of phyto-chemical constituents of this Wild Onion, lessThan i greaterThan Urginea indica lessThan /i greaterThan sps in traditional medicine treatment is discussed. Hence, the formulation of extract of lessThan i greaterThan Urginea indica lessThan /i greaterThan ' needs to be purified using biophysical techniques towards development of a potential drug/ lead molecule against microbial infection, inflammation and wound healing respectively. Panduranga Murthy, G Mamtharani, D.r Tejas, T.S And Niranjan M. Suarlikerimath Liliaceae; Wild onion; Urginea indica Phyto-chemical, Physico-chemical analysis; anti-bacterial activity, Antioxidant activity 230-237