10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 3 2011 (July - September) Methanol and ethyl acetate (stem-bark) extracts of lessThan i greaterThan Raphiostylis beninensis lessThan /i greaterThan were investigated for their phytochemical, antibacterial and cytotoxic properties. Phytochemical analysis of ethyl acetate extracts of lessThan i greaterThan R lessThan /i greaterThan . lessThan i greaterThan beninensis lessThan /i greaterThan revealed alkaloids (1.10 ± 0.20 mg/kg), flavonoids (6.10 ± 0.10 mg/kg), saponins (5.30 ±0.15 mg/kg) and tannins (2.10 ± 0.20 mg/kg). Methanol of extract lessThan i greaterThan R lessThan /i greaterThan . lessThan i greaterThan beninensis lessThan /i greaterThan contained alkaloids (1.50 ±0.10 mg/kg), flavonoids (6.24 ± 0.20 mg/kg), saponins (7.50 ±0.10 mg/kg) and tannins (1.32 ± 0.03 mg/kg). The stem bark methanol and ethyl acetate extracts of lessThan i greaterThan Raphiostylis beninensis lessThan /i greaterThan inhibited all tested strains lessThan i greaterThan Escherichia coli, Bacillus subtilis, Salmonella typhii and Staphyllococcus aureus lessThan /i greaterThan at 20 mg/ml and 50 mg/ml respectively. The brine shrimp lethality test on the methanol and ethyl acetate extracts of lessThan i greaterThan Raphiostylis beninensis lessThan /i greaterThan revealed cytotoxic activities with LC lessThan sub greaterThan 50 lessThan /sub greaterThan of 3.20 and 2.50 µg/ml. Lasisi, A. A., Folarin, O. M. , Dare, E. O , Akinloye, O. A. And Fisuyi, M. O. Raphiostylis beninensis, Antibacterial Activity, Cytotoxic Property, Phytochemical, Methanol Extract, Ethyl Acetate Extract 489-495