<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 2 Issue 3</issue_number>
<issue_period>2011 (July - September)</issue_period>
<title>Serum Hs-Crp And Uric Acid As Indicator Of Severity In Preeclampsia </title>
<abstract>The aim of the present study is to correlate hs-CRP and uric acid levels in preeclamptic women. This study was performed on three groups; mild preeclampsia (n=17), severe preeclampsia (n=13) and healthy pregnant women as controls (n=30). Hs-CRP and uric acid levels were measured in maternal serum by latex turbidimetric method and Uricase-PAP method respectively. In this study we found serum hs-CRP and Uric acid levels were higher in preeclamptic women (3.733±1.096, 8.007±1.077) as compared to normotensive pregnant women (1.216±0.552, 5.50±1.103). Similarly, serum hs-CRP and uric acid levels were significantly elevated in women with severe preeclampsia (4.769±0.807, 9.042±0.650) than mild preeclampsia cases. The positive and significant correlations were found in hs-CRP/Blood Pressure, Uric Acid /Blood Pressure and hs-CRP/Uric Acid. Our results shows that serum hs-CRP and Uric Acid levels have increased as disease progressed from mild to severe condition. Therefore, hs-CRP can be an additional marker to predict severity of disease.</abstract>
<authors>Anil Bargale, Jayashree V. Ganu, Dhiraj J. Trivedi, Nitin Nagane, Rakesh Mudaraddi, Aparna Sagare</authors>
<keywords>Preeclampsia, hs-CRP, Uric acid, Inflammation</keywords>
<pages>340-345</pages>
</article>
</Journal>
