10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 3 2011 (July - September) Radionuclides and metals have posed a great threat to the sustenance of life on earth. These are released by various anthropogenic activities and get accumulated without being eliminated. This environmental hazard can be alleviated by the microbes with the bioleaching property. The present study was designed to isolate microbes that help in the bioremediation of various metals and radionuclides from the sites of Indian Rare Earths Limited (IREL), Berhampur,Orissa. The isolated microbes lessThan b greaterThan lessThan i greaterThan Deinococcus radiodurans and Rhizopus lessThan /i greaterThan lessThan /b greaterThan have been shown to grow well in media supplemented with varied concentrations of different metals . lessThan b greaterThan lessThan i greaterThan Deinococcus radiodurans lessThan /i greaterThan lessThan /b greaterThan was found to be the toughest bacterium to tolerate the radiations and is utilized for in situ bioremediation of radioactive waste by producing higher amount of alkaline phosphatase enzyme and the only fungus lessThan b greaterThan lessThan i greaterThan Rhizopus lessThan /i greaterThan lessThan /b greaterThan studied in this work was helpful in uranium precipitation. S.P.S. Bisht, B.Praveen, Amrita Panda And Sisir Das Radio nuclides,Metals,Bioremediation ,IREL,Alkaline phosphatase,Radiations 416-422