10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 3 2011 (July - September) New some Schiff bases and their Co(II), Ni(II) and Cu(II) complexes formed by the condensation of 2-acetonaphthone with 2-Amino-4-chlorophenol (AACP), 2-amino-4-methylbenzothiazole (AABT) and 2-aminothiazole (ACAT). These compounds have been characterized by elemental analysis, FT-IR, FAB-mass, molar conductance, electronic spectra, ESR and magnetic susceptibility. FAB-mass data show degradation pattern of the complexes. All the complexes are colored and stable towards air and moisture. The complexes exhibit coordination number to be 4 and 6. The Schiff base and metal complexes show a good activity against the bacteria; lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan , lessThan i greaterThan Escherichia coli lessThan /i greaterThan and lessThan i greaterThan B. subtilis lessThan /i greaterThan and fungi lessThan i greaterThan Aspergillus niger lessThan /i greaterThan and lessThan i greaterThan Candida albicans. lessThan /i greaterThan The antimicrobial results also indicate that the metal complexes are better antimicrobial agents as compared to the Schiff bases. A.P. Mishra And D.K. Mishra C Synthesis, FAB-mass, IR, UV-Vis, ESR, Biological activities 430-439