10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 3 2011 (July - September) The present investigation was conducted to evaluate the antibacterial efficacy of five medicinal plants against lessThan i greaterThan Propionibacterium acnes lessThan /i greaterThan . The various solvent extracts of herbs namely lessThan i greaterThan Azadirachta indica, Vitex negundo, Annona squamosa, lessThan /i greaterThan lessThan i greaterThan Cymbopogon citratus lessThan /i greaterThan and lessThan i greaterThan Terminalia chebula lessThan /i greaterThan were prepared by decoction method. The antiacne potential of various solvent extracts of herbs were tested along with the standard Clindamycin in a dose dependant manner by disc diffusion method. The results of the study found that aqueous and ethanolic extracts of lessThan i greaterThan Terminalia chebula lessThan /i greaterThan exhibited the outstanding antiacne activity when compared to all other herbal extracts. Moderate zone of inhibition was observed in the medicinal plants namely lessThan i greaterThan Azadirachta indica, Vitex negundo lessThan /i greaterThan and lessThan i greaterThan Annona squamosa lessThan /i greaterThan . Inhibition zone was not detectable in any of the solvent extracts of lessThan i greaterThan Cymbopogon citratus lessThan /i greaterThan . The findings of this study have identified that lessThan i greaterThan Terminalia chebula lessThan /i greaterThan acts as the promising source of antiacne agent which could be useful in the treatment of acne vulgaris. K. P. Balakrishnan, Nithya Narayanaswamy, Punai Subba, Poornima E. H.2 Propionibacterium acnes, Terminalia chebula, clindamycin, disc diffusion method, acne vulgaris 476-481